FPPS

Farnesyl pyrophosphate synthase;Farnesyl pyrophosphate synthase; Isoform 2 of Farnesyl pyrophosphate synthase

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • FDPS

UniProt ID

  • P14324

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