Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • FAAP100

UniProt ID

  • Q0VG06

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