FNTA

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • FNTA

UniProt ID

  • P49354

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