Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (PubMed:34405687). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (By similarity).

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • FLNC

UniProt ID

  • Q14315

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