Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • FHOD1

    UniProt ID

    • Q9Y613

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