Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • FAAP24

UniProt ID

  • Q9BTP7

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