In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • FAM168A

    UniProt ID

    • Q92567

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