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EST3

Carboxylesterase 3

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CES3

UniProt ID

  • Q6UWW8
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