ENTP1

Isoform 6 of Ectonucleoside triphosphate diphosphohydrolase 1; Isoform 2 of Ectonucleoside triphosphate diphosphohydrolase 1;Ectonucleoside triphosphate diphosphohydrolase 1

Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable) (PubMed:8529670, PubMed:8626624, PubMed:8955160, PubMed:8996251). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (PubMed:8955160, PubMed:8996251).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ENTPD1

UniProt ID

  • P49961
  • P49961-6

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