Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • DUOX1

UniProt ID

  • Q9NRD9

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