Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • DSC2

UniProt ID

  • Q02487

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