DPS1

All trans-polyprenyl-diphosphate synthase PDSS1; Isoform 3 of All trans-polyprenyl-diphosphate synthase PDSS1

Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone (PubMed:16262699). Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9)and ubiquinone-10 (Q10) respectively (PubMed:16262699). The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (PubMed:16262699).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PDSS1

    UniProt ID

    • Q5T2R2

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