Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (PubMed:32325220). Hydrolyzes cystinyl-bis-glycine (PubMed:32325220). ; Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappaB inflammatory signaling pathway.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • DPEP2

UniProt ID

  • Q9H4A9

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