DCAF5

Isoform 2 of DDB1- and CUL4-associated factor 5; Isoform 3 of DDB1- and CUL4-associated factor 5;DDB1- and CUL4-associated factor 5

Is a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex (CRL4) (PubMed:29691401, PubMed:30442713). The complex CRL4-DCAF5 is involved in the ubiquitination of a set of methylated non-histone proteins, including SOX2, DNMT1 and E2F1 (PubMed:29691401, PubMed:30442713).

Associated with:

Alanine Transaminase
Alkaline Phosphatase
Aspartate Transaminase
B12
Basophils
BMI
Breast Cancer
C Reactive Protein
Calcium
Calcium Albumin Ratio
Cancer
Chronic Lymphocytic Leukemia And Small Lymphocytic Lymphoma
Chronik Kidney Diesase
Diastolic Blood Pressure
Eosinophils
Erythrocyte Sedimentation Rate
Ferritin
Folate
FT3 FT4 Ratio
Gamma Glutamyltransferase
Glucose
Granulocytes
HbA1c
Heartrate
Hematocrit
Hemoglobin
High Density Lipoprotein Cholesterol
Hypertension
Iron
Kidney Cancer
Kidney Failure
Knee Osteoarthritis
Lactate Dehydrogenase
Low Density Lipoprotein Cholesterol
Low Grade B Cell Lymphoma
Lymphocytes
Metabolic Syndrome
Monocytes
Neutrophils
Platelet
Prostate Cancer
Psoriasis
Red Blood Cell Count
Severe Obesity (BMI > 35)
Sleep Apnea
Sleep Disorders
Systemic Lupus
Systolic Blood Pressure
Thyroid FT3
Total Cholesterol
Total Fat
Total Lean Muscle
Transferrin Saturation
Triglyceride
Troponin T
Type 2 Diabetes
Uric Acid
Vitamin D
Weight
White Blood Cell
Protein Ubiquitination

Matrix Type

Tissue/Cells

Gene Symbol

DCAF5

UniProt ID

Q96JK2
Q96JK2-3

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DCAF5

Isoform 2 of DDB1- and CUL4-associated factor 5; Isoform 3 of DDB1- and CUL4-associated factor 5;DDB1- and CUL4-associated factor 5

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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