CTRO

Isoform 4 of Citron Rho-interacting kinase;Citron Rho-interacting kinase; Isoform 3 of Citron Rho-interacting kinase;Isoform 4 of Citron Rho-interacting kinase

Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CIT

UniProt ID

  • O14578
  • O14578-4

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