CRLS1

Cardiolipin synthase (CMP-forming); Isoform 2 of Cardiolipin synthase (CMP-forming)

Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CRLS1

UniProt ID

  • Q9UJA2

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