COA6

Cytochrome c oxidase assembly factor 6 homolog; Isoform 3 of Cytochrome c oxidase assembly factor 6 homolog; Isoform 2 of Cytochrome c oxidase assembly factor 6 homolog

Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • COA6

    UniProt ID

    • Q5JTJ3
    • Q5JTJ3-3

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