Required for normal hearing (PubMed:24781754). Necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Required for the proper localization of PTPRQ and RDX to the stereocilium base during postnatal maturation of hair bundles (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions (PubMed:15184393, PubMed:18028448). Required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:20335315). Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens (By similarity).
