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CDN2A

Isoform 5 of Cyclin-dependent kinase inhibitor 2A;Cyclin-dependent kinase inhibitor 2A

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CDKN2A

UniProt ID

  • P42771
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