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CDC45

Cell division control protein 45 homolog; Isoform 3 of Cell division control protein 45 homolog; Isoform 2 of Cell division control protein 45 homolog

Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CDC45

UniProt ID

  • O75419
  • O75419-3
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