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CC120

Isoform 4 of Coiled-coil domain-containing protein 120; Isoform 5 of Coiled-coil domain-containing protein 120; Isoform 2 of Coiled-coil domain-containing protein 120; Isoform 3 of Coiled-coil domain-containing protein 120;Coiled-coil domain-containing protein 120

Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092). Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (PubMed:28422092). Recruits NIN and CEP170 to centrosomes (PubMed:28422092). Also required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • CCDC120

    UniProt ID

    • Q96HB5
    • Q96HB5-3
    • Q96HB5-4
    • Q96HB5-5
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