CATD

Cathepsin D

Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Associated with:

Acute Ischaemic Heart Diseases
Acute Kidney Injury
Acute Pancreatitis
Acute Renal Failure
Alanine Transaminase
Albumin
Alcohol Dependence
Alkaline Phosphatase
Angina Pectoris
Anxiety
Apolipoprotein A
Apolipoprotein B
Arterial Embolism And Thrombosis
Arteriosclerosis
Aspartate Transaminase
Asthma
Atherosclerosis
Autoimmune Disease
B Cell Disorders
Basal Metabolic Rate
Basophils
Bicarbonate
BMI
Bronchiectasis
C Reactive Protein
Calcium
Calcium Albumin Ratio
Cancer
Cellulitis
Chrohns Disease
Chronic Ischaemic Heart Disease
Chronic Obstructive Pulmonary Disease
Chronic Renal Failure
Chronic Viral Hepatitis
Chronik Kidney Diesase
Colon Cancer
Colorectal Cancer
Coronary Artery Disease
Creatinine
Cystatin C
Daily Pain
Decubitus Ulcer
Depression
Diaphragmatic Hernia
Diastolic Blood Pressure
Disorder Of Lipoprotein Metabolism
Diverticular Disease
Emphysema
Eosinophils
Erythrocyte Sedimentation Rate
Estimated Glomerular Filtration Rate
Ferritin
Fibromyalgia
Fluid Intelligence
Folate
FT3 FT4 Ratio
Gallstones
Gamma Glutamyltransferase
Gastric Ulcer
Gastritis And Duodenitis
Gastroesophageal Reflux
Gestational Diabetes
Glucose
Gout
Granulocytes
HbA1c
Heart Failure
Heartrate
Height
Hemoglobin
Hepatic Failure
Hepatocellular Carcinoma
High Density Lipoprotein Cholesterol
Hypertension
IgA
IGF1
Insomnia
Iron
Kidney Failure
Lactate Dehydrogenase
Leukocytes
Lipase
Lipoprotein A
Liver Cirrhosis
Low Density Lipoprotein Cholesterol
Lung Cancer
Lymphocytes
Lymphoproliferative Diseases
Magnesium
Metabolic Acidosis
Metabolic Syndrome
Monocytes
Myocardial Infarction
Neutrophils
Nicotine Dependence
Oesophageal Varices
Oesophagitis
Panic Disorder
Parkinsons Disease
Peripheral Vascular Disease
Persistent Mood Affective Disorders
Personality Disorders
Phneumonia
Phobias
Phosphate
Physical Activity
Platelet
Pneumonia
Polyneuropathy
Prostate Cancer
Psoriasis
Red Blood Cell Count
Reduced Echo Ejection Fraction
Respiratory Alkalosis
Respiratory Failure
Reticulocytes
Rheumatoid Arthritis
Septicaemia
Severe Obesity (BMI > 35)
Sleep Apnea
Sleep Disorders
Sodium
Stroke
Systolic Blood Pressure
Testosterone
Thyroid FT3
Thyroid FT4
Total Bilirubin
Total Cholesterol
Total Lean Muscle
Transferrin Saturation
Triglyceride
Type 2 Diabetes
Urea
Uric Acid
Urine Glucose
Urine Protein
Vitamin D
Waist Circumference
Waist Hip Ratio
Weight
White Blood Cell
Whole Body Fat
Complement
P53 Pathway

Matrix Type

Plasma
Tissue/Cells

Gene Symbol

CTSD

UniProt ID

P07339

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CATD

Cathepsin D

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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