CASPC

Isoform 7 of Inactive caspase-12; Isoform 5 of Inactive caspase-12;Inactive caspase-12

May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF (PubMed:15129283). May lack protease activity (Probable).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CASP12

UniProt ID

  • Q6UXS9
  • Q6UXS9-7

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