CACB2

Isoform 2e of Voltage-dependent L-type calcium channel subunit beta-2;Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2f of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2cN4 of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2c of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2a of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2h of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2cN2 of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2g of Voltage-dependent L-type calcium channel subunit beta-2; Isoform 2b of Voltage-dependent L-type calcium channel subunit beta-2

Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (By similarity). Plays a role in shifting voltage dependencies of activation and inactivation of the channel (By similarity). May modulate G protein inhibition (By similarity). May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (PubMed:36424916). Involved in membrane targeting of the alpha-1 subunit CACNA1C (PubMed:17525370).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • CACNB2

    UniProt ID

    • Q08289
    • Q08289-2
    • Q08289-3
    • Q08289-4
    • Q08289-5
    • Q08289-6
    • Q08289-7
    • Q08289-8
    • Q08289-9

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