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CA2D2

Isoform 5 of Voltage-dependent calcium channel subunit alpha-2/delta-2; Isoform 4 of Voltage-dependent calcium channel subunit alpha-2/delta-2; Isoform 2 of Voltage-dependent calcium channel subunit alpha-2/delta-2; Isoform 3 of Voltage-dependent calcium channel subunit alpha-2/delta-2;Voltage-dependent calcium channel subunit alpha-2/delta-2

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G) (PubMed:15111129, PubMed:23339110). Overexpression induces apoptosis.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • CACNA2D2

UniProt ID

  • Q9NY47
  • Q9NY47-3
  • Q9NY47-4
  • Q9NY47-5
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