Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity). ; [BH3-interacting domain death agonist p15]: Induces caspase activation and apoptosis (PubMed:15661737, PubMed:32029622). Allows the release of cytochrome c (PubMed:32029622). ; [Isoform 1]: Induces ICE-like proteases and apoptosis. ; [Isoform 2]: Induces ICE-like proteases and apoptosis. ; [Isoform 3]: Does not induce apoptosis. ; [Isoform 4]: Induces ICE-like proteases and apoptosis.
