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ATS2

A disintegrin and metalloproteinase with thrombospondin motifs 2

Cleaves the propeptides of type I and II collagen prior to fibril assembly (By similarity). Does not act on type III collagen (By similarity). Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity (PubMed:31152061).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ADAMTS2

UniProt ID

  • O95450
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