ARHGB

Rho guanine nucleotide exchange factor 11; Isoform 2 of Rho guanine nucleotide exchange factor 11;Isoform 2 of Rho guanine nucleotide exchange factor 11

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ARHGEF11

UniProt ID

  • O15085
  • O15085-2

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