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AN13B

Ankyrin repeat domain-containing protein 13B; Isoform 2 of Ankyrin repeat domain-containing protein 13B

Ubiquitin-binding protein that specifically recognizes and binds ‘Lys-63’-linked ubiquitin. Does not bind ‘Lys-48’-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • ANKRD13B

    UniProt ID

    • Q86YJ7
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