Ubiquitin-binding protein that specifically recognizes and binds ‘Lys-63’-linked ubiquitin. Does not bind ‘Lys-48’-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • ANKRD13A

    UniProt ID

    • Q8IZ07

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