AFAD

Isoform 1 of Afadin; Isoform 6 of Afadin; Isoform 5 of Afadin; Isoform 3 of Afadin; Isoform 2 of Afadin;Afadin;Isoform 2 of Afadin

Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton (PubMed:11024295). May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (PubMed:30463011).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • AFDN

    UniProt ID

    • P55196
    • P55196-1
    • P55196-2
    • P55196-3
    • P55196-5
    • P55196-6

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