AF10

Isoform 1 of Protein AF-10;Protein AF-10

Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 ‘Lys-79’ dimethylation (H3K79me2) and gene activation (PubMed:26439302).

Associated with:

Spermatogenesis

Matrix Type

Tissue/Cells

Gene Symbol

MLLT10

UniProt ID

P55197

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AF10

Isoform 1 of Protein AF-10;Protein AF-10

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the AF10 Assay

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