ACAP1

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • ACAP1

    UniProt ID

    • Q15027

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