AADAT

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Isoform 2 of Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • AADAT

UniProt ID

  • Q8N5Z0

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