2A5B

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; Isoform Beta-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PPP2R5B

UniProt ID

  • Q15173

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