LIPA1;LIPA4;LIPA3;LIPA2

Liprin-alpha-2; Liprin-alpha-4;Liprin-alpha-3; Liprin-alpha-1

Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed:30021165).

    Matrix Type

    • Plasma

    Gene Symbol

    • PPFIA2

    UniProt ID

    • O75145
    • O75335
    • Q13136

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