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ZBT14

Zinc finger and BTB domain-containing protein 14

Transcriptional activator of the dopamine transporter (DAT), binding it’s promoter at the consensus sequence 5′-CCTGCACAGTTCACGGA-3′. Binds to 5′-d(GCC)(n)-3′ trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • ZBTB14

    UniProt ID

    • O43829
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