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WWC3

Protein WWC3

Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway. Enhances phosphorylation of LATS1 and YAP1 and negatively regulates cell proliferation and organ growth due to a suppression of the transcriptional activity of YAP1, the major effector of the Hippo pathway.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • WWC3

    UniProt ID

    • Q9ULE0
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