WDR20

Isoform 2 of WD repeat-containing protein 20; Isoform 5 of WD repeat-containing protein 20;WD repeat-containing protein 20; Isoform 4 of WD repeat-containing protein 20; Isoform 7 of WD repeat-containing protein 20; Isoform 6 of WD repeat-containing protein 20

Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336). Regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus (PubMed:30466959).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • WDR20

    UniProt ID

    • Q8TBZ3
    • Q8TBZ3-4
    • Q8TBZ3-5
    • Q8TBZ3-6
    • Q8TBZ3-7

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