VP13A

Isoform 3 of Intermembrane lipid transfer protein VPS13A; Isoform 2 of Intermembrane lipid transfer protein VPS13A; Isoform 4 of Intermembrane lipid transfer protein VPS13A;Intermembrane lipid transfer protein VPS13A;Intermembrane lipid transfer protein VPS13A

Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids (PubMed:34830155). Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria (PubMed:30741634). Negatively regulates lipid droplet size and motility (PubMed:30741634). Required for efficient lysosomal protein degradation (PubMed:30709847).

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • VPS13A

UniProt ID

  • Q96RL7
  • Q96RL7-3
  • Q96RL7-4

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