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UBP47

Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 47; Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 47;Ubiquitin carboxyl-terminal hydrolase 47;Ubiquitin carboxyl-terminal hydrolase 47;Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 47

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • USP47

UniProt ID

  • Q96K76
  • Q96K76-4
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