U2AF1

Splicing factor U2AF 35 kDa subunit;Isoform 2 of Splicing factor U2AF 35 kDa subunit

Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3′-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • U2AF1

UniProt ID

  • Q01081
  • Q01081-2

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