TRI43;TR43B

Tripartite motif-containing protein 43;Tripartite motif-containing protein 43B

E3 ligase that regulates nuclear lamina integrity and the association of viral chromatin with transcriptionally-active host chromatin. Acts thereby as a herpesvirus-specific antiviral factor and mediates the ubiquitination-dependent proteasomal degradation of PCNT.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • TRIM43

UniProt ID

  • A6NCK2

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