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TRIM4

E3 ubiquitin-protein ligase TRIM4; Isoform Beta of E3 ubiquitin-protein ligase TRIM4;E3 ubiquitin-protein ligase TRIM4; Isoform Gamma of E3 ubiquitin-protein ligase TRIM4

E3 ubiquitin-protein ligase. Mediates ‘Lys-63’-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn’t lead to proteasomal degradation but seems to enhance IFN induction.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • TRIM4

UniProt ID

  • Q9C037
  • Q9C037-3
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