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TNF13;TNF12

Isoform TWE-PRIL of Tumor necrosis factor ligand superfamily member 12; Isoform 4 of Tumor necrosis factor ligand superfamily member 13; Isoform Beta of Tumor necrosis factor ligand superfamily member 13; Tumor necrosis factor ligand superfamily member 13; Isoform 5 of Tumor necrosis factor ligand superfamily member 13

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • TNFSF12

UniProt ID

  • O43508-2
  • O75888-2
  • O75888-4
  • O75888-5
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