DIC

Mitochondrial dicarboxylate carrier; Isoform 2 of Mitochondrial dicarboxylate carrier

Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane (PubMed:29211846). Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes. Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity (By similarity).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SLC25A10

UniProt ID

  • Q9UBX3

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