SCYL1

Isoform 2 of N-terminal kinase-like protein;N-terminal kinase-like protein; Isoform 3 of N-terminal kinase-like protein; Isoform 4 of N-terminal kinase-like protein; Isoform 2 of N-terminal kinase-like protein;N-terminal kinase-like protein

Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652). ; Isoform 6 acts as a transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • SCYL1

UniProt ID

  • Q96KG9
  • Q96KG9-2
  • Q96KG9-3
  • Q96KG9-4

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