RIPR1

Isoform 3 of Rho family-interacting cell polarization regulator 1; Isoform 2 of Rho family-interacting cell polarization regulator 1;Rho family-interacting cell polarization regulator 1; Isoform 4 of Rho family-interacting cell polarization regulator 1

Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • RIPOR1

UniProt ID

  • Q6ZS17
  • Q6ZS17-3
  • Q6ZS17-4

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