MRPP3

Mitochondrial ribonuclease P catalytic subunit; Isoform 2 of Mitochondrial ribonuclease P catalytic subunit

Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5′-ends (PubMed:18984158, PubMed:25953853, PubMed:34715011). The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5′-ends (PubMed:25953853).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PRORP

    UniProt ID

    • O15091

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