PREX1

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PREX1

UniProt ID

  • Q8TCU6

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